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HGH Saizen 24 IU


Manufacturer: Merck Serono, Switzerland.

Substance: Somatropin.

Package: 8mg 24IU.

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Saizen [somatropin (rDNA origin) for injection] steps in when the body doesn’t produce enough growth hormone on its own. Saizen is a human growth hormone produced by recombinant DNA technology. It is a type of treatment called growth hormone replacement therapy and is available by prescription only. The structure of the growth hormone used in treatment is identical to the growth hormone produced by the pituitary gland.

Saizen is used for growth hormone therapy to replace the hormone that the body fails to produce on its own. It works to stimulate skeletal growth, increase the number and size of skeletal muscle cells, influence the size and function of internal organs, and has important effects on metabolism.

Treatment may not only help a body grow in height, but will also play an important role in stimulating the liver and other tissues to secrete IGF-1, a protein which supports muscle growth and metabolic functions.


What is Saizen [somatropin (rDNA origin) for injection]?

Saizen [somatropin (rDNA origin) for injection] is a prescription medicine indicated for the treatment of growth hormone deficiency (GHD) in children and adults:
1- to increase growth rate in children with growth failure and who produce low amounts of growth hormone.
2- to replace growth hormone in adults because of either a deficiency that started as a child or started as an adult due to pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma

As with any prescription medicine, your doctor will do a complete health evaluation prior to prescribing Saizen and will monitor your progress and possible side effects during the course of treatment.
Important Risk Information

Who should not take Saizen?

Saizen should not be used in children and adults with any of the following medical conditions because serious side effects can occur:

    a critical illness caused by certain types of heart or stomach surgery, serious injury or a sudden and severe breathing problem (respiratory failure)
    cancer or other tumors
    certain types of eye problems caused by diabetes
    allergies to any of the ingredients in the medicine including benzyl alcohol
    Prader-Willi syndrome who are severely overweight or have a history of breathing problems including sleep apnea

Saizen should also not be used in children who have completed growth.

Other possible side effects of Saizen are:

    return of tumor or cancerous growths
    headaches, changes in vision, nausea or vomiting (these may be symptoms of raised pressure in the brain which requires immediate medical attention)
    hip and knee pain or a limp in children, that can be a sign of slipped capital femoral epiphysis
    worsening of pre-existing curvature of the spine in children (scoliosis)
    intense pain and tenderness in the abdomen as consequence of an inflammation of the pancreas (pancreatitis)
    high blood sugar (hyperglycemia/diabetes)

Never share a Saizen needle with another person, even if the needle is changed. Sharing of needles between patients may pose a risk of transmission of infection. EMD Serono medical devices should only be used according to the instruction manual and only after proper training from a healthcare provider. For children, an adult should supervise the use of EMD Serono medical devices.

Specific References